Epithelioid Hemangioendothelioma of the Liver: A Case Report

Epithelioid hemangioendothelioma of the liver (EHE) is a rare primary solid tumor of vascular origin [1-4]. EHE represents about 0.4% of all sarcomas and only 20% develop in the liver [5]. It occurs in a non-cirrhotic liver and its pathogenesis remains unknown. The involvement is often multinodular and may mimic metastases of a primary extrahepatic lesion and may delay the diagnosis. The clinical and biological signs are non-specific. Anatomopathological diagnosis can be difficult, requiring the precious help of immunohistochemistry. We report the clinical case of a 22-year-old patient admitted with febrile right hypochondrial pain, peritoneal and pleural effusion syndrome with a severe alteration of general condition. The diagnosis of hepatic EHE was proven on immunohistochemical study of the liver biopsy. The evolution was marked by the death of the patient.