Aamer, Nasrullah and Memon, Beenish Ghafar and Rashid, Abdul and Makwana, Dayaram and Memon, Shahzad and Memon, Waseem Raja (2021) Association of Sub-Clinical Hypothyroidism with Abnormal Levels of Lipid in the Population of Nawabshah, Pakistan. Journal of Pharmaceutical Research International, 33 (59A). pp. 452-458. ISSN 2456-9119
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Abstract
Aims: Aim of this investigation was to access the association of dyslipidemia with subclinical hypothyroidism.
Methodology: In this cross-sectional investigation, 1948 participants were recruited. Two groups were made; participants up to 18 years were in group A and Subjects over 18 years were incorporated in group 2. They were subdivided into control, subclinical hypothyroid 1, and subclinical hypothyroid 2. SPSS 21 was used for data analysis.
Results: Data of 1619 individuals were analyzed. The mean age of Group A participants was 12.79 ± 2.779, and the mean age of Group B participants was 42.58 ± 18.012. The prevalence of subclinical hypothyroid was found at 13.5 %. Significant differences have been observed while comparing Group A and Group B (P <0.001). Free tetraiodothyronine and Free triiodothyronine also showed a significant difference in both groups. (P<0.05). No significant difference between mean Thyroid-stimulating hormone levels was observed (P>0.05). No significant association between Controls and High-density Lipid values was found between Controls and subclinical hypothyroid.
Conclusion: We conclude that subclinical hypothyroidism leads to increased dyslipidemia. Lower Serum total cholesterol and low-density lipid levels were detected among children and participants under the age of 18 with Thyroid-stimulating hormone greater than 10 mIU/L. Thyroid-stimulating hormone less than 10.0 mIU/L had no lipid abnormalities in subclinical hypothyroid participants.
Item Type: | Article |
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Subjects: | Library Keep > Medical Science |
Depositing User: | Unnamed user with email support@librarykeep.com |
Date Deposited: | 24 Mar 2023 10:24 |
Last Modified: | 10 Feb 2024 04:10 |
URI: | http://archive.jibiology.com/id/eprint/78 |