Low Dose Biophotonic Treatment Enhances Oxygen Saturation and Hematologic Parameters

The prevalence of diabetes, especially Type 2 diabetes or NIDDM is approaching epidemic proportions in much of Westernized society as the populations continue to age and as the prevalence of obesity, overweight conditions, and their common pathophysiologic sequelae emerge in parallel, while effective therapeutic options often place a strain on available resources. Applications of controlled UV irradiation however represent a novel potential approach in the treatment of a broad variety of metabolic conditions including NIDDM. The aim of the study is to examine the impact of Low Dose Biophotonic Treatment on Hematologic Parameters and Oxygen Saturation. The wide-ranging effects of healthful vs. damaging consequences of UV irradiation on key physiologic parameters are reviewed in this paper. The effects are largely dependent on the wavelengths encountered, the absolute intensity and duration of the exposure, the tissues exposed, and whether the UV effects were delivered via in vivo or as an extracorporeal exposure in vitro typically performed with freshly obtained heparinized aliquots of whole blood. The mechanism for the biophotonic-mediated alterations in hemoglobin glycation remain speculative however, and may be due to a pH induced reversal or limitation at the level of the committed step in the glycation process as depicted in Fig. 4 as a result of the biophotonic excitation. While damaging effects of high UV intensity may include irreversible irradiation damage to key cellular and molecular components, controlled low dosages of UV irradiation delivered via a conventional biophotonic apparatus at specific, controlled wavelengths can deliver beneficial effects on blood oxygenation, tissue repair, immune responses, glycemia, and glycated hemoglobin (HbA1c) concentrations. HbA1c is an important diagnostic marker for the effectiveness of diabetes management. Studies reviewed demonstrate increases in blood oxygenation and corresponding decreases in HbA1c concentrations following nominal low dose biophotonic treatment at selected wavelengths and indicate that the application of this therapy extends beyond its more commonly applied applications in the treatment and control of infectious illnesses. Oxygen availability in combination with ‘good’ ROS responses is a crucial component of a healthy wellbeing and immune responses and are important constituents of the broad spectrum of beneficial effects of UV- biophotonic therapy, and signal the reemergence of an old and reliable treatment for both old and emerging diseases.