Antimicrobial and Antioxidant Properties of Hedranthera barteri Leaf and Root Extracts

Plants have been a good source of alternative therapy, due to the increasing use of plants for therapeutic purposes, there is a need to evaluate their medicinal constituents. This study assessed the phytochemical potential, antioxidant, and antimicrobial proprieties of Hedranthera barteri extracts. Qualitative and quantitative procedures were used to evaluate the phytochemical constituents. 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picryl/hydrazine (DPPH) was use to assay for radical scavenging properties of Hedranthera barteri extracts. The scavenging activities of nitric oxide (NO) radical, and its total reducing capacity methods, were used to analyze the antioxidant potentials of Hedranthera barteri extracts. Serial dilution and disc diffusion methods were used to assess the minimum inhibitory concentration and antimicrobial activity of Hedranthera barteri extracts. The result of this study revealed that extracts of Hedranthera barteri possess abundant phytochemical constituents as well as high antioxidant potential. The data also showed that the root and leaf extracts of Hedranthera barteri possess very strong antibacterial potential against Staphylococcus spp, Streptococcus spp, Neisseria spp, Escherichia coli, Pseudomonas spp, and Enterobacter spp. The root extract had an inhibition zone of 11.00±1.00 to 22.00±1.00 mm while the leaf extract inhibition zone was 8.00±1.00 to 18.67±1.53 mm. This study disclosed the antimicrobial and antioxidant properties of Hedranthera barteri extracts. For further studies, we will explore the characterization of bioactive constituents, a critical step forward to determine the potential therapeutics of these extracts.